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Overview
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The parathyroid glands function within the endocrine system to promote blood calcium homeostasisthrough controlled release of parathyroid hormone (PTH). This process involves the synthesis andsecretion of PTH by activated parathyroid chief cells during conditions of hypocalcemia. With theanatomical proximity to the thyroid and capacity of associated neoplasms of the parathyroid to mimicthyroid tumors, challenges can arise in distinguishing between these types of abnormalities. In caseswhere there is uncertainty about a tumor being of parathyroid origin, immunohistochemical evaluationusing anti-PTH can be of value.
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