Anti-Human PD1 antibody

Anti-Human PD1 antibody

Catalog Number:
IGA1028245STJ
Mfr. No.:
STJ16100414
Price:
$1,397
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      • Overview
        • Programmed death-1 (PD1) is a member of the CD28 family of receptors that includes CD28, cytotoxicT-lymphocyte-associated antigen 4 (CTLA-4), inducible costimulator (ICOS), and B-and T-lymphocyteattenuator. These receptors play a role in the cellular immune response. For example, CD28 serves asa costimulatory receptor that enhances T-cell activation, whereas CTLA-4 serves as an inhibitor of T-cellactivation. PD1 also has an inhibitory function on T cells and B cells, and is important in peripheraltolerance. There are at least 2 ligands for PD1, PD-L1, and PD-L2, which are expressed on a range ofcells.

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      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          human
          Clone
          NAT105
          Conjugate
          Unconjugated
          Formulation
          1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
          Storage
          Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Spermatogenesis-Associated Protein 2 (Gene ID:9825; UniProt:Q9UM82)

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC 1:25 – 1:100

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