Name: Anti-Human p21 antibody
Price: 1331.00 USD

Overview
- P21 is one of the inhibitors of the phosphorylation of the cyclin-cdk complex. p21, which is an inhibitorof G1 cdks, suppresses the cell cycle and inhibits DNA synthesis. Although p21 is induced by p53 andinhibits cdk (cyclin-dependent kinase) activity, there was virtually no correlation between theexpression of p21 and that of p53; this finding was consistent with two reports, though anotherreported an inverse correlation between the expression of p21 and that of p53. p53ìindependentexpression of p21 might account for the discrepancy between the expression of p53 and that of p21. Itis expressed in normal human tissue and a wide array of tumors.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1 kappa
  
  Reactivity
  
  human
  
  Clone
  
  DCS-60.2
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Cyclin-Dependent Kinase Inhibitor 1; Cdk-Interacting Protein 1; Melanoma Differentiation-Associated Protein 6; Mda-6; P21 (Gene ID:1026; UniProt:P38936)
  
  * For research use only

Applications

Application	Dilutions
IHC	1:50 – 1:200

Anti-Human p21 antibody