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Overview
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GCDFP-15 is a glycoprotein localized in the apocrine metaplastic epithelium lining breast cysts and inapocrine glands in the axilla, vulva, eyelid, ear canal, and in salivary glands. GCDFP-15 positivity is seenin breast carcinomas. On the other hand, colorectal carcinomas, lung carcinoma, mesotheliomas rarelystain with this antibody. Because of its specificity for breast carcinoma, this antibody is often helpful indistinguishing metastasis of unknown primary.
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