Name: Anti-Human Cytokeratin 5 antibody
Price: 1408.00 USD

Overview
- Cytokeratin 5 is an intermediate filament protein of 58 kD molecular weight within the cytokeratinfamily. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous andglandular epithelia, myoepithelia, and mesothelium. Anti-cytokeratin 5 has been reported useful in thedifferential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma.Epithelioid mesotheliomas are strongly positive in almost all cases, but a minority of pulmonaryadenocarcinomas will show focal immunoreactivity. Almost all squamous cell carcinomas, half oftransitional carcinomas, and many undifferentiated large cell carcinomas immunostain with anti-CK 5.Anti-CK 5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation.Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled withanti-CK. This antibody, along with anti-CK 14, has found application in identifying basal-like breastcarcinoma.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human
  
  Clone
  
  EP1601Y
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Keratin-Type II Cytoskeletal 5; 58 Kda Cytokeratin; Cytokeratin-5; Ck-5; Keratin-5; K5; Type-II Keratin Kb5 (Gene ID:3852; UniProt:P13647)
  
  * For research use only