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Overview
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Cytokeratins 8 &18 (CK 8 & 18) are expressed in most simple epithelia (e.g. thyroid, breast, gastrointestinal tract, and respiratory tract). Anti-CK 8 & 18 have been reported to stain mostadenocarcinomas and squamous cell carcinomas, but not some well-differentiated squamous cellcarcinomas. Cytokeratin 8 & 18 have been reported to be useful markers for identifying Paget cells, colorectal carcinoma metastases, 5 and gastric cancer micro metastases.
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