Name: Anti-Cytokeratin 8 antibody
Price: 1068.00 USD

Overview
- Cytokeratin 8, a member of the Type II family of cytokeratins, is typically expressed in simpleepithelium. The dimerization of cytokeratin 8 with cytokeratin 18 (labeled by 35 betaH11) in thecytoplasm of simple epithelial cells allows for the formation of an intermediate filament cytoskeletalframework. This structure plays a role in the maintenance of cellular structural integrity and alsofunctions in promoting signal transduction and cellular differentiation processes. Additionally, thepresence of cytokeratin 8 has been detected in neoplastic epithelia, including glandular epithelium thatcan be found in prostate carcinoma. Positive immunoreactivity with anti-cytokeratin 8 is a usefulindicator for the identification of normal and neoplastic epithelial tissues.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgM kappa
  
  Reactivity
  
  human
  
  Clone
  
  35betaH11
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Keratin-Type II Cytoskeletal 8; Cytokeratin-8; Ck-8; Keratin-8; K8; Type-II Keratin Kb8 (Gene ID:3856; UniProt:P05787)
  
  * For research use only

Applications

Application	Dilutions
IHC	1: 100 – 1:500

$833

$1,183

$930

$1,381