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Overview
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The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
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Overview
Immunohistochemistry of paraffin-embedded mouse liver using HNF4A Antibody (STJ24060) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat pancreas using HNF4A Antibody (STJ24060) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using HNF4A antibody (STJ24060) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-HNF4A antibody
Anti-HNF4A antibody
Catalog Number:
A001034152STJ
Mfr. No.:
STJ24060
Price:
$297
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