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Overview
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GCDFP-15 is a 15 kD glycoprotein which is localized in the apocrine metaplastic epithelium lining breastcysts and in apocrine glands in the axilla, vulva, eyelid, ear canal, and in salivary glands. GCDFP-15positivity is seen in breast carcinomas. On the other hand, colorectal carcinomas, lung carcinoma, mesotheliomas rarely stain with this antibody. Because of its specificity for breast carcinoma, thisantibody is often helpful in distinguishing metastasis of unknown primary.
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- Properties
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Overview