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Overview
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Gamma tubulin is a protein encoded by the TUBG1 gene which is approximately 51, 1 kDa. Gamma tubulin is localised to the cytoplasm and cytoskeleton. It is involved in the regulation of PLK1 activity at G2/M transition, Sertoli-Sertoli cell junction dynamics and organelle biogenesis and maintenance. This protein falls under the tubulin superfamily. It localizes to the centrosome where it binds to microtubules as part of a complex known as the gamma-tubulin ring complex and is required for microtubule formation and progression of the cell cycle. Gamma tubulin is expressed in the skin, nervous system, lung, kidney and muscle. Mutations in the TUBG1 gene may result in cortical dysplasia. STJ97744 was developed from clone 4A4 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of gamma tubulin.
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Overview
Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using gamma Tutulin Mouse mAb diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded Human-liver-cancer tissue. 1, Gamma Tubulin Mouse monoclonal antibody (4A4) was diluted at 1:200 (4°C, overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval (>98°C, 20min). 3, Secondary antibody was diluted at 1:200 (room tempeRature, 30min). Negative control was used by secondary antibody only.
Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using gamma Tutulin Mouse mAb diluted at 1:200.
Immunofluorescence analysis of human-lung tissue. 1, Gamma Tubulin Mouse monoclonal antibody (4A4) (red) was diluted at 1:200 (4°C, overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).3, Picture B: DAPI (blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B
Anti-Gamma Tubulin antibody
Anti-Gamma Tubulin antibody
Catalog Number:
A001053112STJ
Mfr. No.:
STJ97744
Price:
$224
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