Name: Anti-Gamma Tubulin antibody
Price: 224.00 USD

Overview
- Gamma tubulin is a protein encoded by the TUBG1 gene which is approximately 51, 1 kDa. Gamma tubulin is localised to the cytoplasm and cytoskeleton. It is involved in the regulation of PLK1 activity at G2/M transition, Sertoli-Sertoli cell junction dynamics and organelle biogenesis and maintenance. This protein falls under the tubulin superfamily. It localizes to the centrosome where it binds to microtubules as part of a complex known as the gamma-tubulin ring complex and is required for microtubule formation and progression of the cell cycle. Gamma tubulin is expressed in the skin, nervous system, lung, kidney and muscle. Mutations in the TUBG1 gene may result in cortical dysplasia. STJ97744 was developed from clone 4A4 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of gamma tubulin.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human
  
  Clone
  
  4A4
  
  Immunogen
  
  synthetic peptide derived from Gamma Tubulin
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Tubulin Gamma-1 Chain; Gamma-1-Tubulin; Gamma-Tubulin Complex Component 1; Gcp-1 (Gene ID:7283; UniProt:P23258)
  
  * For research use only