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Overview
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The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
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Overview
Immunohistochemistry of paraffin-embedded human uterine cancer using FLNA antibody (STJ110205) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon muscle using FLNA antibody (STJ110205) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human breast cancer using FLNA antibody (STJ110205) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using FLNA antibody (STJ110205) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 30s.
Anti-FLNA antibody
Anti-FLNA antibody
Catalog Number:
A001017055STJ
Mfr. No.:
STJ110205
Price:
$297
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