Anti-EHMT1 antibody

Catalog Number:

A001017564STJ

Mfr. No.:

STJ110811

Price:

$297

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Overview
- The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC-and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human EHMT1 (NP_079033. 4).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Histone-Lysine N-Methyltransferase Ehmt1; Euchromatic Histone-Lysine N-Methyltransferase 1; Eu-Hmtase1; G9a-Like Protein 1; Glp; Glp1; Histone H3-K9 Methyltransferase 5; H3-K9-Hmtase 5; Lysine N-Methyltransferase 1d (Gene ID:79813; UniProt:Q9H9B1)
  
  * For research use only