Name: Anti-RNF34 antibody
Price: 297.00 USD

Overview
- The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human RNF34 (NP_079402. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  E3 Ubiquitin-Protein Ligase Rnf34; Caspase Regulator Carp1; Caspases-8 And-10-Associated Ring Finger Protein 1; Carp-1; Fyve-Ring Finger Protein Momo; Human Ring Finger Homologous To Inhibitor Of Apoptosis Protein; Hrfi; Ring Finger Protein 34; Ring Finger Protein Riff; Ring-Type E3 Ubiquitin Transferase Rnf34 (Gene ID:80196; UniProt:Q969K3)
  
  * For research use only

Applications

Application

WB

Application	Dilutions
WB	1:500-1:2000

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