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Overview
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This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
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- Properties
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Overview
Immunofluorescence analysis of NIH-3T3 cells using DKK3 Polyclonal Antibody (STJ23387) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded rat heart using DKK3 antibody (STJ23387) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using DKK3 antibody (STJ23387) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of mouse brain, using DKK3 antibody (STJ23387) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-DKK3 antibody
Anti-DKK3 antibody
Catalog Number:
A001033766STJ
Mfr. No.:
STJ23387
Price:
$297
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