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Overview
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This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
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Overview
Immunohistochemistry of paraffin-embedded rat kidney using DLC1 antibody (STJ23388) at dilution of 1:200 (40x lens).
Western blot analysis of extracts of mouse lung, using DLC1 antibody (STJ23388) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.
Anti-DLC1 antibody
Anti-DLC1 antibody
Catalog Number:
A001033767STJ
Mfr. No.:
STJ23388
Price:
$297
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