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Overview
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs.
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Overview
Immunofluorescence analysis of HeLa cells using DDX20 antibody (STJ28380). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human colon using DDX20 Antibody (STJ28380) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using DDX20 Antibody (STJ28380) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human amygdalitis using DDX20 Antibody (STJ28380) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using DDX20 antibody (STJ28380) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90s.
Anti-DDX20 antibody
Anti-DDX20 antibody
Catalog Number:
A001036481STJ
Mfr. No.:
STJ28380
Price:
$297
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