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Overview
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The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
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- Properties
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Overview
Immunofluorescence analysis of HeLa cells using DBN1 antibody (STJ28449). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using DBN1 antibody (STJ28449) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-DBN1 antibody
Anti-DBN1 antibody
Catalog Number:
A001036547STJ
Mfr. No.:
STJ28449
Price:
$297
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