Anti-Cytokeratin, Pan antibody

Anti-Cytokeratin, Pan antibody

Catalog Number:
IGA1029571STJ
Mfr. No.:
STJ180390
Price:
$359
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      • Overview
        • Anti‐cytokeratin clone OSCAR (CK OSCAR) demonstrates a broad spectrum of cytokeratin reactivity. In normal tissues, OSCAR is reactive with most epithelial types, including bile ducts and hepatocytes in liver, bladder epithelium, breast ducts, bronchial epithelium, endometrium, intestinal epithelium of stomach, duodenum, ileum, colon, rectum, pancreas, ovarian epithelium, pancreatic acini, pituitary acini, pneumocytes, prostate, thyroid, skin (positive on the basal layer and negative on the superficial layers of squamous epithelium), and apocrine and sweat glands. In tumors, OSCAR is reactive with most carcinomas, including breast, transitional cell (TCC), renal cell (RCC), lung adenocarcinoma, lung small cell, lung squamous cell, endometrial, prostate, ovarian, hepatocellular (HCC), colorectal CA, stomach and thyroid. It is negative in certain normal tissues, including brain, lymphocytes and all cells of hematolymphoid origin, muscle, brain, nerves, endothelium and in certain tumors including most melanomas, sarcomas, lymphomas, primitive neuroectodermal tumors (PNET)/Ewing’s and gastrointestinal stromal tumors (GIST). Positivity has been seen on some dendritic cells in lymph nodes, some endothelia, and some muscle cells.

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      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG2a kappa
          Reactivity
          human
          Clone
          OSCAR
          Immunogen
          Crude cytokeratin extract prepared from RT‐4 and MCF‐7 cells
          Conjugate
          Unconjugated
          Formulation
          Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
          Storage
          Store at 2-8°C for up to 1 year
          Regulatory Status
          RUO

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC (paraffin) 1:25‐100

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