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Overview
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Cytokeratin 14 is a member of the Type I family of cytokeratins and is generally expressed in the basalcell layer of squamous epithelium. The cytokeratin 14 protein forms a heterotetramer withhomodimers of cytokeratin 5 to contribute to the structural integrity of the intracellular cytoskeletalnetwork. Anti-cytokeratin 14 has immunohistochemical utility as an aid in distinguishing squamous cellcarcinomas from other tumors of epithelial origin.
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