Name: Anti-COX IV antibody
Price: 224.00 USD

Overview
- COX IV is a protein encoded by the COX4I1 gene which is approximately 19, 5 kDa. COX IV is localised to the mitochondrion inner membrane. It is involved in respiratory electron transport, metabolism, gene expression, cardiac muscle contraction, apoptosis and autophagy. It is the terminal enzyme of the mitochondrial respiratory chain and forms a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. COX IV is expressed ubiquitously in human tissue. Mutations in the COX4I1 gene may result in Calvarial hyperostosis. STJ96935 was developed from clone 6C8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous COX IV protein.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human; rat; mouse
  
  Clone
  
  6C8
  
  Immunogen
  
  Recombinant Protein
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Cytochrome C Oxidase Subunit 4 Isoform 1-Mitochondrial; Cytochrome C Oxidase Polypeptide Iv; Cytochrome C Oxidase Subunit Iv Isoform 1; Cox Iv-1 (Gene ID:1327; UniProt:P13073)
  
  * For research use only