Anti-CFLAR antibody

Catalog Number:

A001033595STJ

Mfr. No.:

STJ23109

Price:

$297

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Overview
- The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 161-480 of human CFLAR (NP_001120655. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Casp8 And Fadd-Like Apoptosis Regulator; Caspase Homolog; Cash; Caspase-Eight-Related Protein; Casper; Caspase-Like Apoptosis Regulatory Protein; Clarp; Cellular Flice-Like Inhibitory Protein; C-Flip; Fadd-Like Antiapoptotic Molecule 1; Flame-1; Inhibitor Of Flice; I-Flice; Mach-Related Inducer Of Toxicity; Mrit; Usurpin Cleaved Into-Casp8 And Fadd-Like Apoptosis Regulator Subunit P43-Casp8 And Fadd-Like Apoptosis Regulator Subunit P12 (Gene ID:8837; UniProt:O15519)
  
  * For research use only