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Overview
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This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
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Overview
Immunohistochemistry of paraffin-embedded rat brain using CHAT antibody (STJ23113) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CHAT Rabbit pAb (STJ23113).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 180s.
Anti-CHAT antibody
Anti-CHAT antibody
Catalog Number:
A001033598STJ
Mfr. No.:
STJ23113
Price:
$297
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