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Overview
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This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.
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- Properties
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Overview
Western blot analysis of extracts of various cell lines, using CEACAM3 antibody (STJ23090) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 15s.
Anti-CEACAM3 antibody
Anti-CEACAM3 antibody
Catalog Number:
A001033586STJ
Mfr. No.:
STJ23090
Price:
$297
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