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Overview
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This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
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Overview
Immunohistochemistry of paraffin-embedded human liver cancer using CES1 antibody (STJ23100) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CES1 antibody (STJ23100) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-CES1 antibody
Anti-CES1 antibody
Catalog Number:
A001033589STJ
Mfr. No.:
STJ23100
Price:
$297
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