Anti-CDKN3 antibody

Catalog Number:

A001033582STJ

Mfr. No.:

STJ23083

Price:

$297

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Overview
- The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CDKN3 (NP_001124323. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Cyclin-Dependent Kinase Inhibitor 3; Cdk2-Associated Dual-Specificity Phosphatase; Cyclin-Dependent Kinase Interactor 1; Cyclin-Dependent Kinase-Interacting Protein 2; Kinase-Associated Phosphatase (Gene ID:1033; UniProt:Q16667)
  
  * For research use only