Anti-CDK7 antibody

Catalog Number:

A001021750STJ

Mfr. No.:

STJ114807

Price:

$297

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Overview
- The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-346 of human CDK7 (NP_001790. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Cyclin-Dependent Kinase 7; 39 Kda Protein Kinase; P39 Mo15; Cdk-Activating Kinase 1; Cell Division Protein Kinase 7; Serine/Threonine-Protein Kinase 1; TfIIh Basal Transcription Factor Complex Kinase Subunit (Gene ID:1022; UniProt:P50613)
  
  * For research use only