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Overview
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Reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein(immunoglobulin supergene family) widely expressed on hematopoietic cells.CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinityligand for 2B4 and low affinity ligand for CD2. 2B4-CD48 interaction among NK cells and NK-T cellsregulates cell proliferation. Signaling through CD48 results in eosinophil activation and CD48expression is increased in several infectious diseases.Immunogen: Raji human Burkitt's lymphoma cell line
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