Name: Anti-CD4 antibody
Price: 224.00 USD

Overview
- CD4 is a protein encoded by the CD4 gene which is approximately 51, 1 kDa. CD4 is localised to the cell membrane and endoplasmic reticulum. It is involved in the TGF-beta pathway, PEDF induced signalling and the T-cell receptor signalling pathway. It is a membrane glycoprotein of T-lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. It initiates or augments the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. CD4 is expressed in the blood, cells of the nervous system, liver, pancreas and spleen. STJ96972 was developed from clone 11A1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous CD4 proteins.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human; mouse; rat
  
  Clone
  
  11A1
  
  Immunogen
  
  Synthetic Peptide
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  T-Cell Surface Glycoprotein Cd4; T-Cell Surface Antigen T4/Leu-3; Cd Antigen Cd4 (Gene ID:920; UniProt:P01730)
  
  * For research use only