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Overview
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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded rat kidney using CD151 antibody (STJ22974) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human lung cancer using CD151 antibody (STJ22974) at dilution of 1:200 (40x lens).
Western blot analysis of extracts of mouse skeletal muscle, using CD151 Antibody (STJ22974) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.
Anti-CD151 antibody
Anti-CD151 antibody
Catalog Number:
A001033511STJ
Mfr. No.:
STJ22974
Price:
$297
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