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Overview
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This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
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Overview
Immunohistochemistry of paraffin-embedded rat liver using BUB1 Antibody (STJ22846) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse testis using BUB1 Antibody (STJ22846) at dilution of 1:200 (40x lens).
Western blot analysis of extracts of various cell lines, using BUB1 antibody (STJ22846) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-BUB1 antibody
Anti-BUB1 antibody
Catalog Number:
A001033441STJ
Mfr. No.:
STJ22846
Price:
$297
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