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Overview
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This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human breast cancer using BUB1B antibody (STJ22847) at dilution of 1:200 (40x lens).
Immunofluorescence analysis of NIH-3T3 cells using BUB1B antibody (STJ22847) at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using BUB1B antibody (STJ22847) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-BUB1B antibody
Anti-BUB1B antibody
Catalog Number:
A001033442STJ
Mfr. No.:
STJ22847
Price:
$297
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