Name: Anti-BIRC7 antibody
Price: 297.00 USD

Overview
- This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human BIRC7 (NP_647478. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Baculoviral Iap Repeat-Containing Protein 7; Kidney Inhibitor Of Apoptosis Protein; Kiap; Livin; Melanoma Inhibitor Of Apoptosis Protein; Ml-Iap; Ring Finger Protein 50; Ring-Type E3 Ubiquitin Transferase Birc7 Cleaved Into-Baculoviral Iap Repeat-Containing Protein 7 30kda Subunit; Truncated Livin; P30-Livin; Tlivin (Gene ID:79444; UniProt:Q96CA5)
  
  * For research use only