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Overview
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This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
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- Properties
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Overview
Immunofluorescence analysis of U2OS cells using Bid antibody (STJ22797) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells using Bid antibody (STJ22797) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of NIH/3T3 cells using Bid antibody (STJ22797) at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of HL-60 cells, using Bid Antibody (STJ22797).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.
Anti-Bid antibody
Anti-Bid antibody
Catalog Number:
A001033416STJ
Mfr. No.:
STJ22797
Price:
$297
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