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Overview
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human colon using BMP2 antibody (STJ22811) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using BMP2 antibody (STJ22811) at dilution of 1:200 (40x lens).
Western blot analysis of extracts of various cell lines, using BMP2 Antibody (STJ22811) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-BMP2 antibody
Anti-BMP2 antibody
Catalog Number:
A001033422STJ
Mfr. No.:
STJ22811
Price:
$297
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