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Overview
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Reacts with hCG beta chain, which is specific for hCG. The alpha chain is identical amonghCG, TSH, FSH and LH. While hCG is secreted in large quantities by normal trophoblasts, it is presentonly in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. Besidestrophoblastic tumors e.g. choriocarcinoma, large cell carcinoma, adenocarcinoma and squamous cellcarcinoma of the lung are also positive in 90%, 60% and 20% of cases respectively. In hCG producingtumors, including also certain testicular and embryonic carcinomas, the beta chain is produced inhigher quantities than the alpha or dimeric chains.Immunogen: hCG beta, conjugated to various carrier proteins
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