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Overview
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This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human stomach using ATP7A antibody (STJ110697) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using ATP7A antibody (STJ110697) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver damage using ATP7A antibody (STJ110697) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of 293T cells, using ATP7A antibody (STJ110697) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-ATP7A antibody
Anti-ATP7A antibody
Catalog Number:
A001017450STJ
Mfr. No.:
STJ110697
Price:
$297
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