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Overview
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AR-beta3 is a protein encoded by the ADRB3 gene which is approximately 43, 5 kDa. AR-beta3 is localised to the cell membrane. It is involved in peptide ligand-binding receptors, activation of cAMP-dependent PKA, signalling by GPCR and DAG and IP3 signalling. It mediates catecholamine-induced activation of adenylate cyclase through the action of G proteins and is involved in the regulation of lipolysis and thermogenesis. AR-beta3 is expressed mainly in adipose tissue. Mutations in the ADRB3 gene may be involved in diabetes mellitus and obesity. STJ91728 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of AR-beta3 protein.
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Overview
Western blot analysis of 22RV1 cells using AR-Beta 3 Polyclonal Antibody diluted at 1：1000 Western blot analysis of lysates from K562 cells, using ADRB3 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of K562 cells using AR-Beta 3 Polyclonal Antibody diluted at 1：1000
Anti-AR-Beta antibody
Anti-AR-Beta antibody
Catalog Number:
A001047099STJ
Mfr. No.:
STJ91728
Price:
$224
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