Anti-AIMP1 antibody

Catalog Number:

A001035727STJ

Mfr. No.:

STJ27254

Price:

$297

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Overview
- The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 25-180 of human AIMP1 (NP_001135888. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 1; Multisynthase Complex Auxiliary Component P43 Cleaved Into-Endothelial Monocyte-Activating Polypeptide 2; Emap-2; Endothelial Monocyte-Activating Polypeptide II; Emap-II; Small Inducible Cytokine Subfamily E Member 1 (Gene ID:9255; UniProt:Q12904)
  
  * For research use only