Anti-ACTH antibody

Anti-ACTH antibody

Catalog Number:
IGA1028119STJ
Mfr. No.:
STJ16100288
Price:
$451
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      • Overview
        • ACTH (same as corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary.is specific to synacthen (aa 1-24 of ACTH); does not react with CLIP (aa 17-39 of ACTH).ACTH is also produced by cells of the immune system (T-cells, B-cells, and macrophages) in response tostimuli associated with stress. It's a useful marker in classification of pituitary tumors and the study ofpituitary disease. It reacts with ACTHproducing cells (corticotrophs). It also may react with other tumors(e.g. some small cell lung carcinomas) causing paraneoplastic syndromes by secreting ACTH.Immunogen: ACTH synthetic peptide (aa 1-24) conjugated to KLH

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      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1 kappa
          Reactivity
          human
          Clone
          2F6
          Immunogen
          ACTH synthetic peptide (aa 1-24) conjugated to KLH
          Conjugate
          Unconjugated
          Formulation
          100 µg purified antibody in Phosphate Buffered Saline containing 0.02% sodiumazide.
          Storage
          Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
          Concentration
          100 µg/ml
          Regulatory Status
          RUO

          * For research use only

      • Applications
        • Application
          IHC (paraffin); IHC (frozen); Flow Cytometry; IF; ELISA
        • Application Dilutions
          ELISA solid phase: 0, 1-100 µg/ml, tracer: 0.001-100 µg/ml
          FC 0.5-1.0 µg/million cells in 0.1 ml
          IF 0.5-1.0 µg/ml
          IHC frozen and paraffin sections 2-4 µg/ml for 30 min at RT

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