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Overview
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ACTH (same as corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary.is specific to synacthen (aa 1-24 of ACTH); does not react with CLIP (aa 17-39 of ACTH).ACTH is also produced by cells of the immune system (T-cells, B-cells, and macrophages) in response tostimuli associated with stress. It's a useful marker in classification of pituitary tumors and the study ofpituitary disease. It reacts with ACTHproducing cells (corticotrophs). It also may react with other tumors(e.g. some small cell lung carcinomas) causing paraneoplastic syndromes by secreting ACTH.Immunogen: ACTH synthetic peptide (aa 1-24) conjugated to KLH
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- Properties
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Overview