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Overview
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This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
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- Properties
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Overview
Immunofluorescence analysis of HeLa cells using ABCB8 Polyclonal Antibody (STJ22457) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse heart using ABCB8 antibody (STJ22457) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver damage using ABCB8 antibody (STJ22457) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using ABCB8 antibody (STJ22457) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using ABCB8 antibody (STJ22457) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 5s.
Anti-ABCB8 antibody
Anti-ABCB8 antibody
Catalog Number:
A001033216STJ
Mfr. No.:
STJ22457
Price:
$297
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