Name: Anti-ABCC1 antibody
Price: 297.00 USD

Overview
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 850-960 of human ABCC1 (NP_004987. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Multidrug Resistance-Associated Protein 1; Atp-Binding Cassette Sub-Family C Member 1; Glutathione-S-Conjugate-Translocating Atpase Abcc1; Leukotriene C(4 Transporter; Ltc4 Transporter (Gene ID:4363; UniProt:P33527)
  
  * For research use only