anti-AAV8 (intact particle) mouse monoclonal, ADK8, Biotin Conjugate

Overview
- For characterization of different stages of infection and very useful for analysis of the AAV assembly process. ADK8 specifically reacts with AAV1, AAV3, AAV7, AAV8, AAVrh10, AAVrh74 and Anc80, empty and full capsids. Recognizes a conformational epitope of assembled capsids. Not for use in immunoblotting.
  The ADK8 antibody is used as capture and detection antibody in the AAV8 Titration ELISA (PRAAV8), the AAVrh10 Titration ELISA (PRAAV10) and the AAV8 Xpress ELISA (PRAAV8XP).
  
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  Background
  
  For characterization of different stages of infection and very useful for the analysis of the AAV assembly process. ADK8 specifically reacts with AAV1, AAV3, AAV7, AAV8, AAVrh10, AAVrh74 and Anc80, empty and full capsids. Recognizes a conformational epitope of assembled capsids. Predicted binding site: residues 586-LQQQNT-591 (Gurda et al. 2012). The antibody cannot be used for immunoblotting using denaturing conditions.
  
  Gurda, B. L. et al. Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8. J. Virol. 86, 7739–7751 (2012).
  
  More Details
  
  AAV Antibodies
Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2a kappa
  
  Reactivity
  
  virus (AAV1, AAV3, AAV7, AAV8, AAVrh10, AAVrh74, Anc80)
  
  Clone
  
  ADK8
  
  Immunogen
  
  AAV8 capsids
  
  Purification
  
  protein A affinity chromatography
  
  Conjugate
  
  Biotin
  
  Formulation
  
  lyophilized; reconstitute with 750 µl sterile PBS
  
  Storage
  
  store at 2-8°C
  
  * Research use only