Amoxicillin trihydrate

- Overview
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    Background
    
    Amoxicillin trihydrate is a penicillin-structural similar to ampicillin and broad spectrum antibiotic [1]. Amoxicillin trihydrate has shown an antibacterial spectrum comparable to that of ampicillin and be better absorbed after oral administration. In addition, the antibacterial activity of Amoxicillin trihydrate against approximately 30 isolates each of Escherichia coli, Proteus mirabilis, Kiebsiella, Enterobacter, andindole-positive Proteus specie with the MIC values of 0.01μg/ml, 0.25μg/ml and 50μg/ml for Str.viridans, Bacillus anthracis and P.rettgeri, respectively. Apart from these, Amoxicillin trihydrate has been found to produce substantially higher serum levels than the same dose of ampicillin [1,2,3].
    
    [1] H. Hunter Handsfield, Hugh Clark, James F. Wallace, King K. Holmes and Marvin Turck Amoxicillin, a New Penicillin Antibiotic
    [2] Bodey GP, Nance J. Amoxicillin: in vitro and pharmacological studies. Antimicrob Agents Chemother. 1972 Apr;1(4):358-62.
    [3] Bodey GP, Nance J. Amoxicillin: in vitro and pharmacological studies. Antimicrob Agents Chemother. 1972 Apr;1(4):358-62.
- Properties
  - Categories
    
    Broad spectrum antibiotic
    
    Alternative Name
    
    (2S,5R,6S)-6-((S)-2-amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate
    
    CAS Number
    
    61336-70-7
    
    Molecular Formula
    
    C16H25N3O8S
    
    Molecular Weight
    
    419.45
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    N[[email protected]](C(N[[email protected]]1C(N2[[email protected]@H]1SC(C)(C)[[email protected]@H]2C(O)=O)=O)=O)C3=CC=C(O)C=C3.O.O.O
    
    * For Research Use Only

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

Datasheet

Amoxicillin trihydrate

Background

Documents

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