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Acidic Fibroblast Growth Factor (FGF 1) human (RECOMBINANT)

Acidic Fibroblast Growth Factor (FGF 1) human (RECOMBINANT)

Catalog Number:

P001277804AUS

Mfr. No.:

AUST_GF-040-3; AUST_GF-040-4

Price:

$250

Size:

Quantity:

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- Overview
  - Acidic FGF is a mitogen for cells of mesodermal and neuroectodermal origin, including fibroblasts, endothelial cells, astrocytes, neuroblasts, osteoblasts, and smooth muscle cells. This protein is composed of 140 amino acid residues, and has a 55% homology with basic FGF, including two conserved cysteine residues. Human Acidic FGF is produced by genetically engineered yeast, and purified by heparin-Sepharose affinity chromatography.
    
    Please contact us at for specific academic pricing.
- Properties
  - Type
    
    Recombinant Proteins
    
    Purification
    
    Over 95% pure by HPLC analysis and SDS gel electrophoresis.
    
    Formulation
    
    10 mM Tris-HCl, 1.5 M NaCl, pH 7.0 Concentration: 0.50 mg protein/ml.
    
    Storage
    
    Store at -80°C. It is also possible to keep this protein at low pH (2-5) for a few days.
    
    Molecular Weight
    
    15.5 KDa
    
    Activity
    
    Human acidic FGF is mitogenic for a variety of normal cells in culture including fibroblasts, glial cells, vascular endothelial cells.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Reference
  - 1. Gimenez-Gallego et al., Biochem. Biophys. Res. Comm.(1986) 138:611
    2. Thornton et. al. (1983), Science 222, 623
    3. Gospadorowicz, D. (1987) Methods Enzymol. 147:106

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