Name: Ac2-26
Price: Inquiry

- Overview
  - Annexin/lipocortin 1 mimetic.
    Ac2-26 is the N terminal fragment of annexin A1 and an annexin/lipocortin 1 mimetic. Ac2-26 can inhibit leukocyte extravasation, reduce neutrophil adhesion and emigration, promote detachment of neutrophils from activated mesenteric endothelium and accelerate epithelial wound repair. Local intestinal delivery of Ac2-26 encapsulated within targeted polymeric nanoparticles accelerates healing of murine colonic wounds after biopsy-induced injury.
    
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- Properties
  - Categories
    
    Peptides
    
    Alternative Name
    
    AnxA1 mimetic peptide, Lipocortin-1 (2-26), Annexin-1 (2-26) (human)
    
    Molecular Formula
    
    C141H210N32O44S
    
    Molecular Weight
    
    3089.46
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble to 1 mg/ml in phosphate buffered saline
    
    Other Properties
    
    Sequence: Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH,Ac-AMVSEFLKQAWFIENEEQEYVQTVK
    Modification: N terminal acetyl
    
    Storage
    
    Store dry, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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