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Overview
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Endogenous melanocortin receptor agonist.
alpha-MSH is an endogenous melanocortin receptor agonist with Ki values of 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively. alpha-MSH is primarily a pigmentary hormone of the vertebrates and reduces the concentration of proinflammatory mediators through the induction of cyclic adenosine monophosphate (cAMP), controlling inflammation in the brain and peripheral organs. alpha-MSH also possesses antimicrobial properties.
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Overview
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