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AC 187

AC 187

Catalog Number:
P004516768LIF
Mfr. No.:
PEPTIDE-CG-060
Price:
$381
  • Size:
    1mg
    Quantity:
    Add to Cart:
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      • Overview

        • Selective amylin antagonist.
          AC 187 is an orally active, amylin receptor antagonist with an IC50 of 0.48 nM that displays 38 and 400 fold selectivity over calcitonin and CGRP receptors respectively. Blockade of amylin with AC 187 increases glucagon concentration, accelerates gastric emptying of liquids, and results in an exaggerated post-challenge glycemia. AC 187 alone increases feeding when infused into the area postrema.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Peptides
          Molecular Formula
          C127H205N37O40
          Molecular Weight
          2890.25
          Appearance
          Freeze dried solid
          Purity
          >95% by hplc
          Solubility
          Soluble to 1 mg/ml in water
          Other Properties
          Sequence: Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2,Ac-VLGKLSQELHKLQTYPRTNTGSNTY-NH2
          Modification: N-terminal Ac, C-terminal amide
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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