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10Panx

10Panx

Catalog Number:
P004516766LIF
Mfr. No.:
PEPTIDE-GJ-030
Price:
$238
  • Size:
    1mg
    Quantity:
    Add to Cart:
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      • Overview

        • Blocks pannexin-1 gap junctions.
          10Panx mimics a sequence (WRQAAFVDSY) in the second extracellular loop of Panx1 and is a panx-1 mimetic inhibitory peptide that blocks pannexin 1 gap junctions. 10Panx can inhibit Panx1 hemichannel mediated ATP release and inflammasome activation in astrocytes and macrophages and in vivo, pharmacological blockade of Panx1 hemichannels with 10Panx peptide attenuates the progression of acetaminophen induced hepatotoxicity, neuropathic pain and epilepsy.

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      • Properties
        • Categories
          Peptides
          Alternative Name
          Panx-1 mimetic inhibitory peptide, 10Panx1
          Molecular Formula
          C58H79N15O16
          Molecular Weight
          1242.37
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble to 1 mg/ml in water
          Other Properties
          Sequence: H-Trp-Arg-Gln-Ala-Ala-Phe-Val-Asp-Ser-Tyr-OH,WRQAAFVDSY
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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