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Z-VAD-FMK

Z-VAD-FMK

Catalog Number:
P004516956LIF
Mfr. No.:
PEPTIDE-PI-250
Price:
$275
  • Size:
    1mg
    Quantity:
    Add to Cart:
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      • Overview

        • Pan-caspase inhibitor.
          Z-VAD-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable, irreversible pan-caspase inhibitor. Z-VAD-FMK inhibits caspase processing and apoptosis induction in tumour cells in vitro with an IC50 of 0.0015 – 5.8 mM). Z-VAD-FMK is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Z-VAD-FMK is active in vivo and can inhibit apoptosis in numerous settings.

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          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Peptides
          Alternative Name
          Z-Val-Ala-Asp(OMe)-FMK
          Molecular Formula
          C22H30FN3O7
          Molecular Weight
          467.49
          Appearance
          White lyophilised solid
          Purity
          >98% by TLC
          Solubility
          Soluble to 10 mg/mL in DMSO
          Other Properties
          Sequence: Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone,Z-VAD-FMK
          Modification: Benzyloxycarbonyl (Z) at N terminal, Fluoromethylketone (FMK) at C terminal
          Storage
          Store dry, dark and frozen

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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