WP 1130 , >98% by HPLC

WP 1130 , >98% by HPLC

Catalog Number:
P004517012LIF
Mfr. No.:
PEPTIDE-PI-240
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  • Size:
    10mg
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      • Overview

        • Deubiquitinase (DUB) inhibitor.
          WP 1130, also known as degrasyn, is a cell-permeable deubiquitinase (DUB) inhibitor, able to directly inhibit the DUB activity of USP9x, USP5, USP14, and UCH37. WP 1130 has been shown to downregulate both wild-type and mutant Bcr/Abl without affecting bcr/abl gene expression in chronic myelogenous leukemia (CML) cells. WP 1130 can cause marked anti-proliferative activity and morphological changes in NCH644 and NCH421K glioma stem-like cells.

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      • Properties
        • Categories
          Small Molecules
          Alternative Name
          Degrasyn
          Molecular Formula
          C19H18BrN3O
          Molecular Weight
          384.3
          Appearance
          White solid
          Purity
          >98% by HPLC
          Solubility
          Soluble in DMSO and ethanol
          Other Properties
          Sequence: (2E)‹-3-‹(6-‹bromo-‹2-‹pyridinyl)‹-‹2-‹cyano-‹N-‹[1S-‹phenylbutyl]‹-2-‹propenamide,(2E)‹-3-‹(6-‹bromo-‹2-‹pyridinyl)‹-‹2-‹cyano-‹N-‹[1S-‹phenylbutyl]‹-2-‹propenamide
          Storage
          Store desiccated, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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